The role of the microbiome in childhood asthma.
Identifieur interne : 000125 ( Main/Exploration ); précédent : 000124; suivant : 000126The role of the microbiome in childhood asthma.
Auteurs : Giovanna Pisi [Italie] ; Valentina Fainardi [Italie] ; Marina Aiello [Italie] ; Giuseppina Bertorelli [Italie] ; Ernesto Crisafulli [Italie] ; Alfredo Chetta [Italie]Source :
- Immunotherapy [ 1750-7448 ] ; 2017.
Descripteurs français
- KwdFr :
- Appareil respiratoire (microbiologie), Asthme (immunologie), Asthme (microbiologie), Asthme (thérapie), Femelle (MeSH), Humains (MeSH), Immunité (MeSH), Immunomodulation (MeSH), Immunothérapie (méthodes), Interactions hôte-pathogène (MeSH), Microbiome gastro-intestinal (immunologie), Microbiote (immunologie), Spécificité d'espèce (MeSH), Spécificité d'organe (MeSH).
- MESH :
- immunologie : Asthme, Microbiome gastro-intestinal, Microbiote.
- microbiologie : Appareil respiratoire, Asthme.
- méthodes : Immunothérapie.
- thérapie : Asthme.
- Femelle, Humains, Immunité, Immunomodulation, Interactions hôte-pathogène, Spécificité d'espèce, Spécificité d'organe.
English descriptors
- KwdEn :
- Asthma (immunology), Asthma (microbiology), Asthma (therapy), Female (MeSH), Gastrointestinal Microbiome (immunology), Host-Pathogen Interactions (MeSH), Humans (MeSH), Immunity (MeSH), Immunomodulation (MeSH), Immunotherapy (methods), Microbiota (immunology), Organ Specificity (MeSH), Respiratory System (microbiology), Species Specificity (MeSH).
- MESH :
- immunology : Asthma, Gastrointestinal Microbiome, Microbiota.
- methods : Immunotherapy.
- microbiology : Asthma, Respiratory System.
- therapy : Asthma.
- Female, Host-Pathogen Interactions, Humans, Immunity, Immunomodulation, Organ Specificity, Species Specificity.
Abstract
It is now well established that the healthy bronchial tree contains a microbiome distinct from that of the upper respiratory tract and that the lung microbiome may be dysregulated in individuals with a chronic respiratory disease, such as asthma. In addition, after birth, gut microbes interact with the host tissue, especially with the lymphatic tissue, thereby guaranteeing efficient immune activation. This review focuses on the available literature on the relationships between the gut microbiome, immune function and asthma in childhood, as well as the therapeutic strategies aimed at acting on the modulation of the microbiome.
DOI: 10.2217/imt-2017-0048
PubMed: 29130800
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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In addition, after birth, gut microbes interact with the host tissue, especially with the lymphatic tissue, thereby guaranteeing efficient immune activation. This review focuses on the available literature on the relationships between the gut microbiome, immune function and asthma in childhood, as well as the therapeutic strategies aimed at acting on the modulation of the microbiome.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29130800</PMID><DateCompleted><Year>2018</Year><Month>06</Month><Day>18</Day></DateCompleted><DateRevised><Year>2018</Year><Month>06</Month><Day>22</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1750-7448</ISSN><JournalIssue CitedMedium="Internet"><Volume>9</Volume><Issue>15</Issue><PubDate><Year>2017</Year><Month>11</Month></PubDate></JournalIssue><Title>Immunotherapy</Title><ISOAbbreviation>Immunotherapy</ISOAbbreviation></Journal><ArticleTitle>The role of the microbiome in childhood asthma.</ArticleTitle><Pagination><MedlinePgn>1295-1304</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.2217/imt-2017-0048</ELocationID><Abstract><AbstractText>It is now well established that the healthy bronchial tree contains a microbiome distinct from that of the upper respiratory tract and that the lung microbiome may be dysregulated in individuals with a chronic respiratory disease, such as asthma. In addition, after birth, gut microbes interact with the host tissue, especially with the lymphatic tissue, thereby guaranteeing efficient immune activation. This review focuses on the available literature on the relationships between the gut microbiome, immune function and asthma in childhood, as well as the therapeutic strategies aimed at acting on the modulation of the microbiome.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Pisi</LastName><ForeName>Giovanna</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Cystic Fibrotic Centre, University Hospital, Parma, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fainardi</LastName><ForeName>Valentina</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Paediatrics Unit, University Hospital, Parma, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Aiello</LastName><ForeName>Marina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Respiratory Disease Unit, Department of Medicine & Surgery, University Hospital, Via Gramsci, 14 - 43100 Parma, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bertorelli</LastName><ForeName>Giuseppina</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Respiratory Disease Unit, Department of Medicine & Surgery, University Hospital, Via Gramsci, 14 - 43100 Parma, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Crisafulli</LastName><ForeName>Ernesto</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Respiratory Disease Unit, Department of Medicine & Surgery, University Hospital, Via Gramsci, 14 - 43100 Parma, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chetta</LastName><ForeName>Alfredo</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Respiratory Disease Unit, Department of Medicine & Surgery, University Hospital, Via Gramsci, 14 - 43100 Parma, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Immunotherapy</MedlineTA><NlmUniqueID>101485158</NlmUniqueID><ISSNLinking>1750-743X</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001249" MajorTopicYN="N">Asthma</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000069196" MajorTopicYN="N">Gastrointestinal Microbiome</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D054884" MajorTopicYN="N">Host-Pathogen Interactions</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007109" MajorTopicYN="N">Immunity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D056747" MajorTopicYN="N">Immunomodulation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007167" MajorTopicYN="N">Immunotherapy</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D064307" MajorTopicYN="N">Microbiota</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009928" MajorTopicYN="N">Organ Specificity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012137" MajorTopicYN="N">Respiratory System</DescriptorName><QualifierName UI="Q000382" MajorTopicYN="Y">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013045" MajorTopicYN="N">Species Specificity</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">asthma</Keyword><Keyword MajorTopicYN="Y">childhood</Keyword><Keyword MajorTopicYN="Y">microbiome</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>11</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>11</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2018</Year><Month>6</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29130800</ArticleId><ArticleId IdType="doi">10.2217/imt-2017-0048</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Italie</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Pisi, Giovanna" sort="Pisi, Giovanna" uniqKey="Pisi G" first="Giovanna" last="Pisi">Giovanna Pisi</name></noRegion><name sortKey="Aiello, Marina" sort="Aiello, Marina" uniqKey="Aiello M" first="Marina" last="Aiello">Marina Aiello</name><name sortKey="Bertorelli, Giuseppina" sort="Bertorelli, Giuseppina" uniqKey="Bertorelli G" first="Giuseppina" last="Bertorelli">Giuseppina Bertorelli</name><name sortKey="Chetta, Alfredo" sort="Chetta, Alfredo" uniqKey="Chetta A" first="Alfredo" last="Chetta">Alfredo Chetta</name><name sortKey="Crisafulli, Ernesto" sort="Crisafulli, Ernesto" uniqKey="Crisafulli E" first="Ernesto" last="Crisafulli">Ernesto Crisafulli</name><name sortKey="Fainardi, Valentina" sort="Fainardi, Valentina" uniqKey="Fainardi V" first="Valentina" last="Fainardi">Valentina Fainardi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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